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kavain biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
(6E)-3,5-dioxo-7-phenylhept-6-enoyl-[styrylpyrone_synthase] <=> 4-hydroxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one + polyketide-[acp] not assigned

4-hydroxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one + NADPH + H+ <=> (E)-5,6-dihydro-4-hydroxy-6-(styryl)pyran-2-one + NADP+ 1.3.1.M26

(E)-5,6-dihydro-4-hydroxy-6-(styryl)pyran-2-one + S-adenosyl-L-methionine <=> (R)-(+)-kavain + S-adenosyl-L-homocysteine + H+ 2.1.1.M66

cinnamoyl-CoA + malonyl-CoA + polyketide-[acp] + H+ <=> (6E)-3,5-dioxo-7-phenylhept-6-enoyl-[styrylpyrone_synthase] + CO2 + CoA not assigned

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